How Is Dna Testing Done

DNA testing is done for many different reasons. DNAAs DNA testing has evolved over time, the testing
evidence can link an alleged criminal to a crime scene.methods have become more precise and are able to
DNA paternity and maternity testing can identify awork with much smaller DNA samples. Early DNA
child's father or mother. DNA relationship testing cantesting was done using dime-size drops of blood.
determine if two individuals are full or half siblings. DNAToday's tests can extract DNA from the back of a
ancestry testing can determine ethnic origins andlicked stamp. The DNA must be extracted from
genealogical roots.whatever sample is provided. DNA must be isolated
How DNA testing is done depends on the resultsand purified before it can be compared. In essence, it
desired and the samples available. DNA fingerprintinghas to be "unlocked" from the cell in which it exists.
(or profiling as it's also known) is the process ofThe cell walls are usually dissolved with a detergent.
analyzing and comparing two DNA samples. OnlyProteins in the cell are digested by enzymes. After this
identical twins have the exact same DNA sequence,process, the DNA is purified, concentrated, and tested.
everyone else's DNA is unique. This makes DNA theDNA testing is done most often today using a process
perfect way to link individuals to each other or tocalled "short tandem repeats," or STR. Human DNA
locations where they have been.has several regions of repeated sequences. These
The entire DNA chain is incredibly long, much to long toregions are found in the same place on the DNA chain,
examine all of it. Human DNA is made up of about 3.3but the repeated sequences are different for each
billion base pairs. The differences between DNAindividual. The "short" tandem repeats (repeated
samples occur only in small segments of the DNA--thesequences of two to five base pairs in length) have
rest of the DNA is pretty much the same. DNA testingbeen proven to provide excellent DNA profiling results.
focuses on those segments that are known to differSTR is highly accurate--the chance of misidentification
from person to person.being one in several billion.